Letrozole
Letrozole 是一种芳香酶抑制剂。CGS 20267 是一种新型非甾体化合物，能够在体外（IC50 为 11.5 nM）和体内（ED50 为 1-3 微克/千克，口服）强效抑制芳香酶。
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Adooq用户使用Letrozole发表的1篇文献
生物活性
| Discription | Letrozole is an Aromatase inhibitor. CGS 20267 is a new non-steroidal compound which potently inhibits aromatase in vitro (IC50 of 11.5 nM) and in vivo (ED50 of 1?€?3 μg/kg p.o.) | |||||
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产品信息
| 目录号 | A10523 |
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| 分子式 | C17H11N5 |
| 分子量 | 285.3 |
| CAS号 | 112809-51-5 |
| SMILES | C1=CC(=CC=C1C#N)C(C2=CC=C(C=C2)C#N)N3C=NC=N3 |
| 其他名称 | CGS 20267, Femara, Piroxicam |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 50 mg/mL (175.25 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 0.5% CMC Na | 9 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 35.05 mL | 175.25 mL | 350.51 mL |
| 0.5 mM | 7.01 mL | 35.05 mL | 70.1 mL |
| 1 mM | 3.51 mL | 17.53 mL | 35.05 mL |
| 5 mM | 0.7 mL | 3.51 mL | 7.01 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 112809-51-5 | 112809-51-5 供应商 | 112809-51-5 花费 | 112809-51-5 生产商 | 订购 112809-51-5 | 112809-51-5 代理商