Leu-AMS
目录号: A19580
LRS inhibitor
Leu-AMS(化合物6),一种亮氨酸类似物,是一种强效的亮氨酸-tRNA合成酶(LRS)抑制剂,其IC50为22.34 nM,它抑制了LRS的催化活性,但不影响亮氨酸诱导的mTORC1激活。
Discription | Leu-AMS (compound 6), a leucine analogue, is a potent inhibitor of leucyl-tRNA synthetase (LRS) with an IC50 of 22.34 nM, which inhibits the catalytic activity of LRS but did not affect the leucine-induced mTORC1 activation. | |||||
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Cell Research |
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目录号 | A19580 |
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分子式 | C16H25N7O7S |
分子量 | 459.48 |
CAS号 | 288591-93-5 |
SMILES | O[C@@H]([C@H]([C@H](N1C=NC2=C1N=CN=C2N)O3)O)[C@H]3COS(=O)(NC([C@@H](N)CC(C)C)=O)=O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2