Lexibulin dihydrochloride
目录号: A21774
tubulin polymerisation 抑制剂
Lexibulin 2Hcl(CYT-997 2Hcl)是一种强效的微管聚合抑制剂,在癌细胞系中的IC50为10-100 nM;在体外和体内具有强大的细胞毒性和血管破坏活性。
Discription | Lexibulin 2Hcl (CYT-997 2Hcl) is a potent tubulin polymerisation inhibitor with IC50 of 10-100 nM in cancer cell lines; with potent cytotoxic and vascular disrupting activity in vitro and in vivo. |
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目录号 | A21774 |
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分子式 | C24H32Cl2N6O2 |
分子量 | 507.46 |
CAS号 | 917111-49-0 |
SMILES | CCC[C@H](NC1=C(C)C=NC(C2=CC=C(NC(NCC)=O)C(OC)=C2)=N1)C3=CN=CC=C3.[H]Cl.[H]Cl |
其他名称 | CYT-997 dihydrochloride, CYT997, CYT 997 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2