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LH 846是酪蛋白激酶（CK）1δ的选择性抑制剂（CK1δ，ε和α的IC50值为290 nM，1.3μM和2.5μM）。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 31.56 mL | 157.82 mL | 315.65 mL |
| 0.5 mM | 6.31 mL | 31.56 mL | 63.13 mL |
| 1 mM | 3.16 mL | 15.78 mL | 31.56 mL |
| 5 mM | 0.63 mL | 3.16 mL | 6.31 mL |
*The above data is based on the productmolecular weight 316.81. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13574 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 316.81 |
| Formula | C16H13ClN2OS |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 639052-78-1 |
| Synonyms | LH-846, LH846 |
| SMILES | CC1=CC2=C(C=C1Cl)N=C(S2)NC(=O)CC3=CC=CC=C3 |
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