Licofelone
Licofelone 是一种双重 COX/LOX 抑制剂，被视为治疗骨关节炎的一种潜在药物。它可能减少与其他仅抑制 COX (环氧合酶) 的非甾体抗炎药物相关的胃肠道毒性。Licofelone 是首个同时抑制这两者的药物。
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Adooq用户使用Licofelone发表的1篇文献
生物活性
| Discription | Licofelone is a dual COX/LOX inhibitor, being considered as a treatment for osteoarthritis. It may reduce the gastrointestinal toxicity associated with other non-steroidal anti-inflammatory drugs, which only inhibit COX (cyclooxygenase). Licofelone is the first drug to inhibit both. | |||||
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| Cell Research |
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产品信息
| 目录号 | A11697 |
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| 分子式 | C23H22ClNO2 |
| 分子量 | 379.88 |
| CAS号 | 156897-06-2 |
| SMILES | CC1(CC2=C(C(=C(N2C1)CC(=O)O)C3=CC=C(C=C3)Cl)C4=CC=CC=C4)C |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 16 mg/mL (42.11 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (7.89 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.32 mL | 131.62 mL | 263.24 mL |
| 0.5 mM | 5.26 mL | 26.32 mL | 52.65 mL |
| 1 mM | 2.63 mL | 13.16 mL | 26.32 mL |
| 5 mM | 0.53 mL | 2.63 mL | 5.26 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 156897-06-2 | 156897-06-2 供应商 | 156897-06-2 花费 | 156897-06-2 生产商 | 订购 156897-06-2 | 156897-06-2 代理商