Lifitegrast

Name: Lifitegrast
SKU: A17299
Price: 175 CNY
Rating: 5 (288 reviews)

目录号: A17299

LFA-1 antagonist

Lifitegrast（SAR 1118）是一种整合素淋巴细胞功能相关抗原-1（LFA-1）拮抗剂；它能够抑制Jurkat T细胞与ICAM-1的结合，其IC50为2.98 nM。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥315.00	现货
25mg	¥595.00	现货
50mg	¥980.00	现货
100mg	¥1,610.00	现货
500mg	¥4,060.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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Data Sheet

SDS

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生物活性

Discription

Lifitegrast (SAR 1118) is an integrin lymphocyte function-associated antigen-1 (LFA-1) antagonist; inhibits Jurkat T cell attachment to ICAM-1 with an IC50 of 2.98 nM.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A17299
分子式	C29H24Cl2N2O7S
分子量	615.478
CAS号	1025967-78-5
SMILES	O=C(O)[C@@H](NC(C1=C(Cl)C2=C(CN(C(C3=CC=C4C=COC4=C3)=O)CC2)C=C1Cl)=O)CC5=CC=CC(S(=O)(C)=O)=C5
其他名称	SAR-1118; SAR 1118; SAR1118; Lifitegrast, brand name: Xiidra.
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	98 mg/mL (159.22 mM)
	Water	Insoluble
	Ethanol	20 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	16.25 mL	81.24 mL	162.48 mL
0.5 mM	3.25 mL	16.25 mL	32.5 mL
1 mM	1.62 mL	8.12 mL	16.25 mL
5 mM	0.32 mL	1.62 mL	3.25 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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