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Linagliptin (BI-1356)

目录号: A11224
DPP-4 抑制剂
Linagliptin 是一种 DPP-4 抑制剂,它能抑制分解肠促胰岛素激素,如胰高血糖素样肽-1(GLP-1)和葡萄糖依赖性胰岛素促进多肽(GIP)的酶。
Grouped product items
规格 价格 库存 数量
50mg
¥210.00
现货
100mg
¥315.00
现货
500mg
¥595.00
现货
1g
¥1,120.00
现货
10mM * 1mL in DMSO
¥315.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
生物活性
Discription Linagliptin is a DPP-4 inhibitor, an enzyme that degrades the incretin hormones glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP).
Targets
Target Value
Cell Research
Cell Line Type Value Description References
产品信息
目录号 A11224
分子式 C25H28N8O2
分子量 472.5
CAS号 668270-12-0
SMILES CC#CCN1C2=C(N=C1N3CCC[C@H](C3)N)N(C(=O)N(C2=O)CC4=NC5=CC=CC=C5C(=N4)C)C
其他名称 BI-1356,Tradjenta,Trajenta
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro (25°C) DMSO 16 mg/mL (33.85 mM)
Water Insoluble
Ethanol 1 mg/mL (2.11 mM)
In vivo 0.5% hydroxyethyl cellulose 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.16 mL 105.82 mL 211.64 mL
0.5 mM 4.23 mL 21.16 mL 42.33 mL
1 mM 2.12 mL 10.58 mL 21.16 mL
5 mM 0.42 mL 2.12 mL 4.23 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

  • Calculator Reset
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