Linifanib (ABT-869)

Name: Linifanib (ABT-869)
SKU: A10025
Price: 245 CNY
Rating: 5 (2 reviews)

目录号: A10025

VEGFR/PDGFR 抑制剂

2 篇发表文献

Linifanib（ABT-869）是一种结构新颖的强效抑制剂，针对RTK、VEGF和PDGF具有显著抑制作用，其IC50分别为针对人类内皮细胞、PDGFR-β、KDR和CSF-1R的0.2、2、4和7 nM。

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥455.00	现货
25mg	¥840.00	现货
50mg	¥1,330.00	现货
100mg	¥1,960.00	现货
200mg	¥3,675.00	现货
500mg	¥5,950.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
更大包装	更多折扣

大包装询价

Notify me when the price drops

全国免运费, 顺丰次日达

重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Linifanib (ABT-869)发表的2篇文献

Ayaka Kojima, .et al. , Xenobiotica, 2022, Jul;52(7):669-675 PMID: 36251932

Li Li, .et al. , Leukemia Res, 2019, 78:12-20 PMID: 30660961

生物活性

Discription

Linifanib (ABT-869) is a structurally novel, potent inhibitor of RTK, VEGF and PDGF with IC50 of 0.2, 2, 4, and 7 nM for human endothelial cells, PDGFR-β, KDR, and CSF-1R, respectively.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10025
分子式	C21H18FN5O
分子量	375.4
CAS号	796967-16-3
SMILES	CC1=CC(=C(C=C1)F)NC(=O)NC2=CC=C(C=C2)C3=C4C(=CC=C3)NN=C4N
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	73 mg/mL (194.45 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5%DMSO+40%PEG 300+5%Tween80+50%ddH2O	9 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.64 mL	133.19 mL	266.38 mL
0.5 mM	5.33 mL	26.64 mL	53.28 mL
1 mM	2.66 mL	13.32 mL	26.64 mL
5 mM	0.53 mL	2.66 mL	5.33 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords: 购买 Linifanib (ABT-869) | Linifanib (ABT-869) 供应商 | Linifanib (ABT-869) 花费 | Linifanib (ABT-869) 生产商 | 订购 Linifanib (ABT-869) | Linifanib (ABT-869) 代理商 | 购买 796967-16-3 | 796967-16-3 供应商 | 796967-16-3 花费 | 796967-16-3 生产商 | 订购 796967-16-3 | 796967-16-3 代理商