Lomerizine dihydrochloride
目录号: A16599
Calcium Channel /TRP5 antagonist
Lomerizine dihydrochloride 是一种针对 L型和T型Ca 2+通道 以及 TRp5通道 的拮抗剂,用于治疗偏头痛和眩晕。
Calcium Channel /TRP5 antagonist
Discription | Lomerizine dihydrochloride is a antagonist at L-type and T-type Ca 2+ channels and TRp5 channels used to treat migraines and vertigo. | ||
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Targets |
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目录号 | A16599 |
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分子式 | C27H32Cl2F2N2O3 |
分子量 | 541.46 |
CAS号 | 101477-54-7 |
SMILES | COC1=CC=C(CN2CCN(C(C3=CC=C(F)C=C3)C4=CC=C(F)C=C4)CC2)C(OC)=C1OC.[H]Cl.[H]Cl |
其他名称 | B 2796, B2796, B-2796, Lomerizine HCl |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | Warmed: 87 mg/mL (160.67 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 45 mg/mL (83.1 mM) | ||
In vivo | 2% DMSO+ddH2O | 4 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 18.47 mL | 92.34 mL | 184.69 mL |
0.5 mM | 3.69 mL | 18.47 mL | 36.94 mL |
1 mM | 1.85 mL | 9.23 mL | 18.47 mL |
5 mM | 0.37 mL | 1.85 mL | 3.69 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2