Lomitapide mesylate
目录号: A16600
MTP 抑制剂
Lomitapide mesylate(AEGR-733;BMS-201038)是一种微粒体甘油三酯转移蛋白(MTP)抑制剂,其体外 IC50 为 8 nM。
Discription | Lomitapide mesylate(AEGR-733; BMS-201038) is an inhibitor of microsomal triglyceride-transfer protein (MTP) wtih in vitro IC50 of 8 nM. |
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目录号 | A16600 |
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分子式 | C40H41F6N3O5S |
分子量 | 789.83 |
CAS号 | 202914-84-9 |
SMILES | O=C(C1(CCCCN2CCC(NC(C3=CC=CC=C3C4=CC=C(C(F)(F)F)C=C4)=O)CC2)C5=C(C6=C1C=CC=C6)C=CC=C5)NCC(F)(F)F.O=S(C)(O)=O |
其他名称 | AEGR-733 mesylate, AEGR733, AEGR 733; BMS-201038 mesylate, BMS 201038, BMS201038 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 91 mg/mL (115.21 mM) | |
Water | Insoluble | ||
Ethanol | 91 mg/mL (115.21 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 12.66 mL | 63.3 mL | 126.61 mL |
0.5 mM | 2.53 mL | 12.66 mL | 25.32 mL |
1 mM | 1.27 mL | 6.33 mL | 12.66 mL |
5 mM | 0.25 mL | 1.27 mL | 2.53 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2