Lomustine (CeeNU)
目录号: A10535
Lomustine 是一种烷化亚硝脲化合物，具有类似于 Carmustine 的抗肿瘤活性，能够引起 DNA 间链交联。
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生物活性
| Discription | Lomustine is an alkylating nitrosourea compound that possesses antitumor activity similar to Carmustine causing DNA interstrand cross-linking. |
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产品信息
| 目录号 | A10535 |
|---|---|
| 分子式 | C9H16ClN3O2 |
| 分子量 | 233.69 |
| CAS号 | 13010-47-4 |
| SMILES | C1CCC(CC1)NC(=O)N(CCCl)N=O |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 40 mg/mL (171.16 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 30% propylene glycol, 5% Tween 80, 65% D5W, pH 4 | 9 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 42.79 mL | 213.96 mL | 427.92 mL |
| 0.5 mM | 8.56 mL | 42.79 mL | 85.58 mL |
| 1 mM | 4.28 mL | 21.4 mL | 42.79 mL |
| 5 mM | 0.86 mL | 4.28 mL | 8.56 mL |
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