LP-261
目录号: A22487
LP-261 是一种新型的 微管蛋白 靶向抗癌药物,它通过结合在 微管蛋白 的秋水仙碱位点上,诱导 G2/M 阶段阻滞。在 NCI60 癌细胞系的筛选中,其平均 GI50 约为 100 nM。
Discription | LP-261 is a novel tubulin targeting anticancer agent that binds at the colchicine site on tubulin, inducing G2/M arrest. Screening in the NCI60 cancer cell lines resulted in a mean GI50 of approximately 100 nM. |
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目录号 | A22487 |
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分子式 | C22H19N3O4S |
分子量 | 421.47 |
CAS号 | 915412-67-8 |
SMILES | CS(=O)(NC1=CC(C(C2=CC=NC(OC)=C2)=O)=CC(C3=CC=CC4=C3C=CN4)=C1)=O |
其他名称 | LP-261, LP 261, LP261, |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2