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LSD1-IN-5 (Compound 4e) is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 121 nM. LSD1-IN-5 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.64 mL | 143.19 mL | 286.39 mL |
| 0.5 mM | 5.73 mL | 28.64 mL | 57.28 mL |
| 1 mM | 2.86 mL | 14.32 mL | 28.64 mL |
| 5 mM | 0.57 mL | 2.86 mL | 5.73 mL |
*The above data is based on the productmolecular weight 349.18. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A20479 |
|---|---|
| M. Wt | 349.18 |
| Formula | C15H13BrN2O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2035912-55-9 |
| SMILES | OC1=C(O)C=C(Br)C(/C=C/C2=CC(/C(N)=N/O)=CC=C2)=C1 |
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