LSN 3213128

Name: LSN 3213128
SKU: A19472
Price: 2205 CNY
Rating: 5 (288 reviews)

目录号: A19472

AICARFT 抑制剂

LSN 3213128 是一种选择性的、非经典的、口服生物可用的抗叶酸药物，具有针对氨基咪唑-4-羧酸核糖核苷酸甲酰基转移酶（AICARFT）的强效和特异性抑制活性，其 IC50 为针对 AICARFT 酶的抑制为16 nM，细胞中为19 nM。具有抗肿瘤活性。

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规格	价格	库存
1mg	¥2,205.00	现货
5mg	¥3,255.00	现货
10mg	¥5,250.00	现货
25mg	¥9,975.00	现货
50mg	¥12,985.00	现货
100mg	¥17,465.00	现货
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Data Sheet

SDS

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生物活性

Discription

LSN 3213128 is a selective, nonclassical, orally bioavailable antifolate with potent and specific inhibitory activity for aminoimidazole-4-carboxamide ribonucleotide formyltransferase (AICARFT), with IC50 of 16 nM for AICARFT enzyme inhibiton and 19 nM in cells. Anti-tumor activity.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A19472
分子式	C17H16FN3O4S2
分子量	409.46
CAS号	1941211-99-9
SMILES	O=C1NC=CC2=C1C=C(NS(=O)(C3=CC=C(N4CC[C@@H](O)C4)S3)=O)C(F)=C2
其他名称	LSN3213128, LSN-3213128
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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