LTURM34
目录号: A19994
DNA-PK inhibitor
LTURM34 是一种特定的 DNA-PK 抑制剂(IC50=34 nM)。LTURM34 对 DNA-PK 比对 PI3K 有 170倍 的选择性。LTURM34 在多种肿瘤细胞系中显示出强大的抗增殖活性。
Discription | LTURM34 is a specific DNA-PK inhibitor (IC50=34 nM). LTURM34 exhibits 170-fold selectivity for DNA-PK over PI3K. LTURM34 shows potent antiproliferative activity in a wide range of tumor cell lines. | ||
---|---|---|---|
Targets |
|
目录号 | A19994 |
---|---|
分子式 | C24H18N2O3S |
分子量 | 414.48 |
CAS号 | 1879887-96-3 |
SMILES | O=C1C2=CC=CC(C3=CC=CC4=C3SC5=C4C=CC=C5)=C2OC(N6CCOCC6)=N1 |
其他名称 | LTURM 34, LTURM-34 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 81 mg/mL (195.42 mM) | |
Water | Insoluble | ||
Ethanol | 4 mg/mL (9.65 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 24.13 mL | 120.63 mL | 241.27 mL |
0.5 mM | 4.83 mL | 24.13 mL | 48.25 mL |
1 mM | 2.41 mL | 12.06 mL | 24.13 mL |
5 mM | 0.48 mL | 2.41 mL | 4.83 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2