Lumefantrine
目录号: A17309
Lumefantrine，也被称为 HSDB 7210，是一种用于治疗急性非并发疟疾的抗疟疾药物。它与阿蒂米辛联合使用以提高疗效。这种组合疗法针对疟原虫属的红细胞阶段发挥作用，可用于治疗由恶性疟原虫和未鉴定疟原虫种类引起的感染，包括在氯喹耐药区域获得的感染。
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生物活性
| Discription | Lumefantrine, also known as HSDB 7210, is an antimalarial agent used to treat acute uncomplicated malaria. It is administered in combination with artemether for improved efficacy. This combination therapy exerts its effects against the erythrocytic stages of Plasmodium spp. and may be used to treat infections caused by P. falciparum and unidentified Plasmodium species, including infections acquired in chloroquine-resistant areas. | ||
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产品信息
| 目录号 | A17309 |
|---|---|
| 分子式 | C30H32Cl3NO |
| 分子量 | 528.94 |
| CAS号 | 82186-77-4 |
| SMILES | CCCCN(CCCC)CC(C1=C2C3=C(C=C(C=C3)Cl)C(=CC4=CC=C(C=C4)Cl)C2=CC(=C1)Cl)O |
| 其他名称 | HSDB 7210; HSDB7210; HSDB-7210; Lumefantrine; Benflumetol. |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 11 mg/mL (20.79 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.91 mL | 94.53 mL | 189.06 mL |
| 0.5 mM | 3.78 mL | 18.91 mL | 37.81 mL |
| 1 mM | 1.89 mL | 9.45 mL | 18.91 mL |
| 5 mM | 0.38 mL | 1.89 mL | 3.78 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 82186-77-4 | 82186-77-4 供应商 | 82186-77-4 花费 | 82186-77-4 生产商 | 订购 82186-77-4 | 82186-77-4 代理商