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Lurasidone (SM-13496)是dopamine D2和5-HT7的拮抗剂，IC50 值分别为 1.68 和 0.495 nM。Lurasidone (SM-13496) 也是 5-HT1A 受体的部分激动剂。
| In vitro | DMSO | 7 mg/mL (14.2 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.3 mL | 101.48 mL | 202.96 mL |
| 0.5 mM | 4.06 mL | 20.3 mL | 40.59 mL |
| 1 mM | 2.03 mL | 10.15 mL | 20.3 mL |
| 5 mM | 0.41 mL | 2.03 mL | 4.06 mL |
*The above data is based on the productmolecular weight 492.7 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11214 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 492.7 |
| Formula | C28H36N4O2S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 367514-87-2 |
| Synonyms | SM13496, SM-13496, SM 13496 |
| SMILES | C1CC[C@H]([C@@H](C1)CN2CCN(CC2)C3=NSC4=CC=CC=C43)CN5C(=O)[C@H]6[C@@H]7CC[C@@H](C7)[C@H]6C5=O |
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