Lurbinectedin
目录号: A18237
Lurbinectedin(PM01183)是一种新型的DNA小沟共价结合剂,具有强大的抗肿瘤活性;分别抑制RMG1和RMG2细胞生长,其IC50值分别为1.25 nM和1.16 nM。
Discription | Lurbinectedin (PM01183) is a new DNA minor groove covalent binder with potent anti-tumour activity; inhibits RMG1 and RMG2 cell growth with IC50 values of 1.25 and 1.16 nM, respectively. |
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目录号 | A18237 |
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分子式 | C41H44N4O10S |
分子量 | 784.88 |
CAS号 | 497871-47-3 |
SMILES | Cc1cc2c(c(c1OC)O)[C@@H]3[C@@H]4[C@H]5c6c(c7c(c(c6OC(=O)C)C)OCO7)[C@@H](N4[C@H]([C@H](C2)N3C)O)COC(=O)[C@@]8(CS5)c9c(c1cc(ccc1[nH]9)OC)CCN8 |
其他名称 | Lurbinectedin; PM01183; PM-01183; UNII-2CN60TN6ZS |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2