LX2761
目录号: A20597
SGLT1/SGLT2 抑制剂
LX2761 是一种化学稳定且有效的 钠依赖性葡萄糖共转运蛋白1(SGLT1)和 SGLT2 的抑制剂,在体外具有对 hSGLT1 和 hSGLT2 的 IC50 分别为 2.2 nM 和 2.7 nM,但在胃肠道(GI)中显示出特异性的 SGLT1 抑制作用。
Discription | LX2761 is chemically stable and potent inhibitor against sodium-dependent glucose cotransporter 1 (SGLT1) and SGLT2 in vitro with IC50s of 2.2 nM and 2.7nM for hSGLT1 and hSGLT2, but displays specific SGLT1 inhibition in the gastrointestinal (GI) tract. | |||||
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Cell Research |
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目录号 | A20597 |
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分子式 | C32H47N3O6S |
分子量 | 601.8 |
CAS号 | 1610954-97-6 |
SMILES | CC1=CC=C([C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](SC)O2)C=C1CC3=CC=C(CCCC(NC(C(NCCN(C)C)=O)(C)C)=O)C=C3 |
其他名称 | LX-2761, LX2761 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2