LXR-623
目录号: A21366
LXRα and full LXRβ 激动剂
LXR-623 是一种能穿透大脑的部分 LXRα 和完全 LXRβ 激动剂，其 IC50 分别为 24 nM 和 179 nM。
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生物活性
| Discription | LXR-623 is a brain-penetrant partial LXRα and full LXRβ agonist, with IC50s of 24 nM and 179 nM, respectively. | |||||
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| Cell Research |
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产品信息
| 目录号 | A21366 |
|---|---|
| 分子式 | C21H12ClF5N2 |
| 分子量 | 422.78 |
| CAS号 | 875787-07-8 |
| SMILES | ClC1=C(CN2N=C(C(C(F)(F)F)=CC=C3)C3=C2C4=CC=C(F)C=C4)C=CC(F)=C1 |
| 其他名称 | WAY 252623, WAY-252623, WAY252623, LXR623, LXR 623 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 76 mg/mL (179.76 mM) | |
| Water | Insoluble | ||
| Ethanol | Warmed: 76 mg/mL (179.76 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.65 mL | 118.26 mL | 236.53 mL |
| 0.5 mM | 4.73 mL | 23.65 mL | 47.31 mL |
| 1 mM | 2.37 mL | 11.83 mL | 23.65 mL |
| 5 mM | 0.47 mL | 2.37 mL | 4.73 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 875787-07-8 | 875787-07-8 供应商 | 875787-07-8 花费 | 875787-07-8 生产商 | 订购 875787-07-8 | 875787-07-8 代理商