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LY-2940094 is a potent, selective and orally available nociceptin receptor (NOP receptor) antagonist with high affinity (Ki=0.105 nM) and antagonist potency (Kb=0.166 nM). LY-2940094 reduces ethanol self-administration in animal models.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 20.79 mL | 103.96 mL | 207.92 mL |
| 0.5 mM | 4.16 mL | 20.79 mL | 41.58 mL |
| 1 mM | 2.08 mL | 10.4 mL | 20.79 mL |
| 5 mM | 0.42 mL | 2.08 mL | 4.16 mL |
*The above data is based on the productmolecular weight 480.96. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A19125 |
|---|---|
| 作用机制 | Antagonist (拮抗剂) |
| M. Wt | 480.96 |
| Formula | C22H23ClF2N4O2S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1307245-86-8 |
| Synonyms | LY 2940094; LY2940094 |
| SMILES | OCC1=CC=CN=C1N2N=C(C)C(CN3CCC4(C5=C(C=C(Cl)S5)C(F)(F)CO4)CC3)=C2 |
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