LY2784544 (Gandotinib)

Name: LY2784544 (Gandotinib)
SKU: A10546
Price: 280 CNY
Rating: 5 (288 reviews)

目录号: A10546

JAK 抑制剂

LY2784544 被确认为对 JAK2-V617F 具有高度选择性，并已进入人类临床试验阶段，用于治疗多种骨髓增生性疾病。

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Grouped product items
规格	价格	库存
5mg	¥280.00	现货
10mg	¥490.00	现货
25mg	¥1,050.00	现货
50mg	¥1,960.00	现货
100mg	¥3,325.00	现货
500mg	¥7,595.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

LY2784544 is identified as being highly selective for JAK2-V617F and has advanced into human clinical trials for the treatment of several myeloproliferative disorders.

Targets

Target	Value

产品信息

目录号	A10546
分子式	C23H25ClFN7O
分子量	469.9
CAS号	1229236-86-5
SMILES	CC1=CC(=NN1)NC2=NN3C(=C(N=C3C(=C2)CN4CCOCC4)C)CC5=C(C=C(C=C5)Cl)F
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	92 mg/mL (195.76 mM)
	Water	Insoluble
	Ethanol	9 mg/mL (19.15 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.28 mL	106.41 mL	212.81 mL
0.5 mM	4.26 mL	21.28 mL	42.56 mL
1 mM	2.13 mL	10.64 mL	21.28 mL
5 mM	0.43 mL	2.13 mL	4.26 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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