LY2801653 (Merestinib)

Name: LY2801653 (Merestinib)
SKU: A12557
Price: 280 CNY
Rating: 5 (1 reviews)

目录号: A12557

c-MET 抑制剂

1 篇发表文献

LY2801653 是一种效力强大的、可口服生物利用度高的小分子 c-MET 激酶抑制剂（Ki= 2 nM）。

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Grouped product items
规格	价格	库存
1mg	¥280.00	现货
2mg	¥385.00	现货
5mg	¥665.00	现货
10mg	¥980.00	现货
25mg	¥1,820.00	现货
50mg	¥3,080.00	现货
100mg	¥4,410.00	现货
500mg	¥9,275.00	现货
*10mM 1mL in DMSO**	¥840.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用LY2801653 (Merestinib)发表的1篇文献

Ji-Eun Kim, .et al. , Immunity, 2022, Dec 13;55(12):2300-2317 PMID: 36473468

生物活性

Discription

LY2801653 is a potent, orally bioavailable, small-molecule inhibitor of c-MET kinase(Ki= 2 nM).

Targets

Target	Value

产品信息

目录号	A12557
分子式	C30H22F2N6O3
分子量	552.53
CAS号	1206799-15-6
SMILES	O=C(C1=CC=C(C)N(C2=CC=C(F)C=C2)C1=O)NC3=CC=C(OC4=CC5=C(N(C)N=C5)C=C4C6=CNN=C6)C(F)=C3
其他名称	LY-2801653, Merestinib
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	88 mg/mL (159.26 mM)
	Water	Insoluble
	Ethanol	88 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.1 mL	90.49 mL	180.99 mL
0.5 mM	3.62 mL	18.1 mL	36.2 mL
1 mM	1.81 mL	9.05 mL	18.1 mL
5 mM	0.36 mL	1.81 mL	3.62 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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