LY3009120

目录号: A16603

pan RAF inhibitor

LY3009120

LY3009120 Chemical Structure

CAS NO. 1454682-72-4

LY3009120 is a pan RAF inhibitor which inhibits BRAFV600E, BRAFWT and CRAFWT with IC50s of 5.8, 9.1 and 15 nM, respectively.

库存: 现货

规格 价格 数量
5 mg
¥ 315.00
10 mg
¥ 546.00
50 mg
¥ 1,610.00
100 mg
¥ 3,220.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

LY3009120 is a pan RAF inhibitor which inhibits BRAFV600E, BRAFWT and CRAFWT with IC50s of 5.8, 9.1 and 15 nM, respectively.
In vitro (25°C) DMSO Warmed: 3 mg/mL (7.06 mM)
Water Insoluble
Ethanol Insoluble
In vivo 0.5% CMC Na 28 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 23.56 mL 117.78 mL 235.57 mL
0.5 mM 4.71 mL 23.56 mL 47.11 mL
1 mM 2.36 mL 11.78 mL 23.56 mL
5 mM 0.47 mL 2.36 mL 4.71 mL

*The above data is based on the productmolecular weight 424.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A16603
作用机制 Inhibitor (抑制剂)
M. Wt 424.51
Formula C23H29FN6O
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 1454682-72-4
Synonyms DP-4978
SMILES O=C(NC1=CC(C2=CC3=CN=C(NC)N=C3N=C2C)=C(C)C=C1F)NCCC(C)(C)C

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