LY317615 (Enzastaurin)

Name: LY317615 (Enzastaurin)
SKU: A10356

目录号: A10356

PKCβ 抑制剂

LY317615 (Enzastaurin) Chemical Structure

CAS NO. 170364-57-5

LY317615（Enzastaurin）是一种有效的，选择性的PKCβ抑制剂，具有抗增殖活性（IC50 =?6 nM）。

库存：现货

规格	价格	数量
10 mg	￥ 280.00
50 mg	￥ 840.00
100 mg	￥ 1,400.00
200 mg	￥ 2,450.00
10mM * 1mL in DMSO	￥ 560.00

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生物活性

LY317615（Enzastaurin）是一种有效的，选择性的PKCβ抑制剂，具有抗增殖活性（IC50 =?6 nM）。

靶点信息

PKCβ (Cell-free assay)	PKCα (Cell-free assay)	PKCγ (Cell-free assay)	PKCε (Cell-free assay)
6 nM	39 nM	83 nM	110 nM

溶解度 *

In vitro (25°C)	DMSO	29 mg/mL (56.24 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	15% Captisol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.39 mL	96.97 mL	193.95 mL
0.5 mM	3.88 mL	19.39 mL	38.79 mL
1 mM	1.94 mL	9.7 mL	19.39 mL
5 mM	0.39 mL	1.94 mL	3.88 mL

*The above data is based on the productmolecular weight 515.6 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10356
作用机制	Inhibitor (抑制剂)
M. Wt	515.6
Formula	C32H29N5O2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	170364-57-5
Synonyms	LY-317615
SMILES	CN1C=C(C2=CC=CC=C21)C3=C(C(=O)NC3=O)C4=CN(C5=CC=CC=C54)C6CCN(CC6)CC7=CC=CC=N7