LY335979 (Zosuquidar 3HCl)

Name: LY335979 (Zosuquidar 3HCl)
SKU: A10549

目录号: A10549

P-gp modulator

Product Citations (1)

LY335979 (Zosuquidar 3HCl) Chemical Structure

CAS NO. 167465-36-3

LY335979 (Zosuquidar trihydrochloride)是一种强效高选择性P-gp抑制剂。

库存：现货

规格	价格	数量
5 mg	￥ 350.00
10 mg	￥ 560.00
50 mg	￥ 1,680.00
100 mg	￥ 2,800.00
10mM * 1mL in DMSO	￥ 861.00

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生物活性

LY335979 (Zosuquidar trihydrochloride)是一种强效高选择性P-gp抑制剂。

靶点信息

P-gp (Cell-free assay)
60 nM(Ki)

溶解度 *

In vitro (25°C)	DMSO	93 mg/mL (145.99 mM)
	Water	21 mg/mL (32.96 mM)
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	15.7 mL	78.49 mL	156.99 mL
0.5 mM	3.14 mL	15.7 mL	31.4 mL
1 mM	1.57 mL	7.85 mL	15.7 mL
5 mM	0.31 mL	1.57 mL	3.14 mL

*The above data is based on the productmolecular weight 637.0 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10549
作用机制	Modulator (调节剂)
M. Wt	637.0
Formula	C32H31F2N3O2.3HCl
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	167465-36-3
Synonyms	LY-335979, Zosuquidar trihydrochloride,RS-33295-198
SMILES	C1CN(CCN1C[C@H](COC2=CC=CC3=C2C=CC=N3)O)C4C5=CC=CC=C5[C@H]6[C@H](C6(F)F)C7=CC=CC=C47.Cl.Cl.Cl