LY364947
目录号: A13446
TGFβR-I 抑制剂
LY364947 是一种二杂芳基取代的吡唑化合物，用作 TGF-βRI (TGF-β 受体 I 激酶) 的选择性、ATP竞争性抑制剂。
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生物活性
| Discription | LY364947 is a diheteroaryl-substituted pyrazole compound used as a selective, ATP-competitive inhibitor of TGF-βRI (TGF-β Receptor I kinase). | |||||
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| Cell Research |
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产品信息
| 目录号 | A13446 |
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| 分子式 | C17H12N4 |
| 分子量 | 272.3 |
| CAS号 | 396129-53-6 |
| SMILES | C1=CC=C2C(=C1)C(=CC=N2)C3=C(NN=C3)C4=CC=CC=N4 |
| 其他名称 | HTS 466284 ,TGF-β RI Kinase Inhibitor |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro (25°C) | DMSO | 1 mg/mL (3.67 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
| In vivo | 4% DMSO+30% PEG 300+ddH2O | 0.71 mg/mL | |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.72 mL | 183.62 mL | 367.24 mL |
| 0.5 mM | 7.34 mL | 36.72 mL | 73.45 mL |
| 1 mM | 3.67 mL | 18.36 mL | 36.72 mL |
| 5 mM | 0.73 mL | 3.67 mL | 7.34 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 396129-53-6 | 396129-53-6 供应商 | 396129-53-6 花费 | 396129-53-6 生产商 | 订购 396129-53-6 | 396129-53-6 代理商