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LY573636 (Tasisulam)是一种有效的抗肿瘤剂，在体外和体内引起多种人实体瘤的生长停滞和凋亡。LY573636诱导的凋亡通过线粒体靶向机制发生。
靶点信息
| Caspase | ||||
| In vitro | DMSO | 73 mg/mL (175.85 mM) | |
| Water | Insoluble | ||
| Ethanol | 73 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 24.09 mL | 120.45 mL | 240.9 mL |
| 0.5 mM | 4.82 mL | 24.09 mL | 48.18 mL |
| 1 mM | 2.41 mL | 12.05 mL | 24.09 mL |
| 5 mM | 0.48 mL | 2.41 mL | 4.82 mL |
*The above data is based on the productmolecular weight 415.11. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13070 |
|---|---|
| 作用机制 | Inducer (诱导剂) |
| M. Wt | 415.11 |
| Formula | C11H6BrCl2NO3S2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 519055-62-0 |
| Synonyms | LY 573636, LY-573636 |
| SMILES | C1=CC(=C(C=C1Cl)Cl)C(=O)NS(=O)(=O)C2=CC=C(S2)Br |
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