Lycopodine
目录号: A18633
Lycopodine,一种从石松孢子中提取的药理学上重要的生物活性成分,通过调节5-脂氧合酶和去极化线粒体膜电位,触发难治性前列腺癌细胞的凋亡,而不调节p53活性。Lycopodine通过激活caspase-3诱导凋亡,从而抑制HeLa细胞的增殖。
Discription | Lycopodine, a pharmacologically important bioactive component derived from Lycopodium clavatumspores, triggers apoptosis by modulating 5-lipoxygenase, and depolarizing mitochondrial membrane potential in refractory prostate cancer cells without modulating p53 activity. Lycopodine inhibits proliferation of HeLa cells through induction of apoptosis via caspase-3 activation. | ||
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目录号 | A18633 |
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分子式 | C16H25NO |
分子量 | 247.38 |
CAS号 | 466-61-5 |
SMILES | O=C1[C@]2([H])[C@]34[C@@](CCCN4CCC2)([H])[C@](C[C@@H](C)C3)([H])C1 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2