Signaling Pathway
ULK1 activator
重要通知：仅供研究使用。我们不向患者销售。
| Discription | LYN-1604 is a potential ULK1 agonist with IC50 of 1.66 μM against MDA-MB-231 cells and it binds to wild-type ULK1 with a binding affinity in the nanomole range (Kd=291.4 nM). The ULK1 (Y89A) mutant protein caused a sharp decrease in binding affinity with lower response and Kd than wild-type ULK1, ULK1 (K50A) and ULK1 (L53A) mutants. | |||||
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| Cell Research |
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| 目录号 | A16848 |
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| 分子式 | C33H43Cl2N3O2 |
| 分子量 | 584.6 |
| CAS号 | 2088939-99-3 |
| SMILES | CC(C)CN(CC(C)C)CC(=O)N1CCN(CC1)CC(C2=C(C=C(C=C2)Cl)Cl)OCC3=CC4=CC=CC=C4C=C3 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | 49 mg/mL (74.52 mM) | |
| Water | 98 mg/mL (149.04 mM) | ||
| Ethanol | 98 mg/mL (149.04 mM) | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.11 mL | 85.53 mL | 171.06 mL |
| 0.5 mM | 3.42 mL | 17.11 mL | 34.21 mL |
| 1 mM | 1.71 mL | 8.55 mL | 17.11 mL |
| 5 mM | 0.34 mL | 1.71 mL | 3.42 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
