Signaling Pathway
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| Discription | Lys01 trihydrochloride (Lys05) is a novel lysosomal autophagy inhibitor with IC50 values of 3.6, 3.8, 6 and 7.9 μM for 1205Lu, c8161, LN229 and HT-29 cell line in the MTT assay. |
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| 目录号 | A21702 |
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| 分子式 | C23H26Cl5N5 |
| 分子量 | 549.75 |
| CAS号 | 1391426-24-6 |
| SMILES | CN(CCNC1=CC=NC2=C1C=CC(Cl)=C2)CCNC3=CC=NC4=CC(Cl)=CC=C43.[H]Cl.[H]Cl.[H]Cl |
| 其他名称 | Lys05 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
| In vitro | DMSO | Warmed: 8 mg/mL (14.55 mM) | |
| Water | Warmed: 3 mg/mL (5.45 mM) | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.19 mL | 90.95 mL | 181.9 mL |
| 0.5 mM | 3.64 mL | 18.19 mL | 36.38 mL |
| 1 mM | 1.82 mL | 9.1 mL | 18.19 mL |
| 5 mM | 0.36 mL | 1.82 mL | 3.64 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
