M8-B (hydrochloride)

Name: M8-B (hydrochloride)
SKU: A22607
Price: 140 CNY
Rating: 5 (288 reviews)

目录号: A22607

TRPM8 拮抗剂

M8-B 是瞬时受体电位黑皮素8（TRPM8）的拮抗剂，能够阻断冷、冰晶素（货号 10137）或薄荷醇在体外的激活（IC50 分别为 7.8、26.9 和 64.3 nM）。

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Grouped product items
规格	价格	库存
1mg	¥140.00	现货
2mg	¥175.00	现货
5mg	¥280.00	现货
10mg	¥420.00	现货
25mg	¥980.00	现货
50mg	¥1,610.00	现货
100mg	¥2,415.00	现货
200mg	¥3,395.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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Data Sheet

SDS

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生物活性

Discription	M8-B is an antagonist of transient receptor potential melastatin 8 (TRPM8) that blocks activation by cold, icilin (Item No. 10137), or menthol in vitro (IC50s = 7.8, 26.9, and 64.3 nM, respectively).

产品信息

目录号	A22607
分子式	C22H24N2O3S.HCl
分子量	433
CAS号	883976-12-3
SMILES	COC(C=C(CN(C(C1=CC=CS1)=O)CCN)C=C2)=C2OCC3=CC=CC=C3.Cl
其他名称	M8B (hydrochloride),M8 B (hydrochloride)
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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