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Macbecin I是一种安沙霉素抗生素化合物，可通过与ATP结合位点结合来抑制Hsp90活性，IC50值为μM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 17.9 mL | 89.5 mL | 179 mL |
| 0.5 mM | 3.58 mL | 17.9 mL | 35.8 mL |
| 1 mM | 1.79 mL | 8.95 mL | 17.9 mL |
| 5 mM | 0.36 mL | 1.79 mL | 3.58 mL |
*The above data is based on the productmolecular weight 558.67. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16050 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 558.67 |
| Formula | C30H42N2O8 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 73341-72-7 |
| SMILES | O=C(C(NC1=O)=C2)C([C@@H]([C@@H](C)C[C@H]([C@H]([C@H](C)/C=C(C)/[C@H]([C@H](/C=C\C=C1/C)C)OC(N)=O)OC)OC)OC)=CC2=O |
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