MAK-683
目录号: A16922
EED PPI 抑制剂
MAK-683 是一种强效的 胚胎外胚层发育蛋白(EED)抑制剂和 多梳抑制复合体 2(PRC2)的变构抑制剂,具有潜在的抗肿瘤活性。
Discription | MAK-683 is a potent inhibitor of embryonic ectoderm development protein (EED) and allosteric inhibitor of polycomb repressive complex 2 (PRC2), with potential antineoplastic activity. | |||||
---|---|---|---|---|---|---|
Cell Research |
|
目录号 | A16922 |
---|---|
分子式 | C20H17FN6O |
分子量 | 376.39 |
CAS号 | 1951408-58-4 |
SMILES | CC1=NC=CC=C1C2=CN=C(NCC3=C(F)C=CC4=C3CCO4)N5C2=NN=C5 |
其他名称 | MAK683, MAK 683 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 20 mg/mL (53.13 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 26.57 mL | 132.84 mL | 265.68 mL |
0.5 mM | 5.31 mL | 26.57 mL | 53.14 mL |
1 mM | 2.66 mL | 13.28 mL | 26.57 mL |
5 mM | 0.53 mL | 2.66 mL | 5.31 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2