Malantide
目录号: A23132
Malantide 是一种合成的十二肽,源自 cAMP 依赖性蛋白激酶(PKA)在磷酸化酶激酶 β-亚单位上的磷酸化位点。Malantide 是 PKA 的高度特异性底物,其 Km 值为 15 μM,并且在各种大鼠组织提取物中显示出超过 90% 的底物磷酸化受蛋白抑制剂(PKI)抑制。Malantide 也是 PKC 的有效底物,其 Km 值为 16 μM。
Discription | Malantide is a synthetic dodecapeptide derived from the site phosphorylated by cAMP-dependent protein kinase (PKA) on the β-subunit of phosphorylase kinase. Malantide is a highly specific substrate for PKA with a Km of 15 μM and shows protein inhibitor (PKI) inhibition >90% substrate phosphorylation in various rat tissue extracts. Malantide is also an efficient substrate for PKC with a Km of 16 μM. |
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目录号 | A23132 |
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分子式 | C72H124N22O21 |
分子量 | 1633.89 |
CAS号 | 86555-35-3 |
Sequence | Arg-Thr-Lys-Arg-Ser-Gly-Ser-Val-Tyr-Glu-Pro-Leu-Lys-Ile |
Sequence shortening | RTKRSGSVYEPLKI |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2