Mavacamten
目录号: A19326
cardiac myosin modulator
Mavacamten 是一种心肌肌球蛋白的调节剂,其 IC50 分别为 490 nM 和 711 nM,针对 牛心脏 和 人心脏。
Discription | Mavacamten is a modulator of cardiac myosin, with IC50s of 490, 711 nM for bovine cardiac and human cardiac, respectively. |
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目录号 | A19326 |
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分子式 | C15H19N3O2 |
分子量 | 273.33 |
CAS号 | 1642288-47-8 |
SMILES | CC(N(C1=O)C(C=C(N[C@H](C2=CC=CC=C2)C)N1)=O)C |
其他名称 | MYK461, MYK 461, MYK-461; SAR439152, SAR 439152, SAR-439152 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 50 mg/mL (182.93 mM) | |
Water | Insoluble | ||
Ethanol | 5 mg/mL (18.29 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 36.59 mL | 182.93 mL | 365.86 mL |
0.5 mM | 7.32 mL | 36.59 mL | 73.17 mL |
1 mM | 3.66 mL | 18.29 mL | 36.59 mL |
5 mM | 0.73 mL | 3.66 mL | 7.32 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2