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Mc-MMAD有效的微管蛋白抑制剂，Monomethyl auristatin D (MMAD)是抗体药物偶联物中的毒素有效载荷；Mc-MMAD是保护基（马来酰亚胺基己酰基）偶联的MMAD。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 10.37 mL | 51.85 mL | 103.71 mL |
| 0.5 mM | 2.07 mL | 10.37 mL | 20.74 mL |
| 1 mM | 1.04 mL | 5.19 mL | 10.37 mL |
| 5 mM | 0.21 mL | 1.04 mL | 2.07 mL |
*The above data is based on the productmolecular weight 964.26. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15156 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 964.26 |
| Formula | C51H77N7O9S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1401963-15-2 |
| Synonyms | Mc MMAD, McMMAD |
| SMILES | CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(CC2=CC=CC=C2)C3=NC=CS3)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)N(C)C(=O)CCCCCN4C(=O)C=CC4=O |
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