MC-Val-Cit-PAB

Name: MC-Val-Cit-PAB
SKU: A20571
Price: 140 CNY
Rating: 5 (288 reviews)

目录号: A20571

MC-Val-Cit-PAB 是一种可被 cathepsin 切割的 ADC linker，用于制造抗体药物偶联物。FDA 批准的药物如 brentuximab vedotin 使用了这种连接器。

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Grouped product items
规格	价格	库存
5mg	¥140.00	现货
10mg	¥175.00	现货
25mg	¥210.00	现货
100mg	¥525.00	现货
250mg	¥980.00	现货
500mg	¥1,225.00	现货
1g	¥1,890.00	现货
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Data Sheet

SDS

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生物活性

Discription

MC-Val-Cit-PAB is a cathepsin cleavable ADC linker that is used for making antibody-drug conjugate. FDA approved drugs such as brentuximab vedotin use this linker.

Targets

Target	Value

产品信息

目录号	A20571
分子式	C28H40N6O7
分子量	572.65
CAS号	159857-80-4
SMILES	CC(C)[C@@H](C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(CO)C=C1)=O)=O)NC(CCCCCN2C(C=CC2=O)=O)=O
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	98 mg/mL (171.13 mM)
	* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	17.46 mL	87.31 mL	174.63 mL
0.5 mM	3.49 mL	17.46 mL	34.93 mL
1 mM	1.75 mL	8.73 mL	17.46 mL
5 mM	0.35 mL	1.75 mL	3.49 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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