MC1568

Name: MC1568
SKU: A10560
Price: 175 CNY
Rating: 5 (5 reviews)

目录号: A10560

HDAC 抑制剂

5 篇发表文献

MC1568 是 HDAC 抑制剂的一种，它通过改变细胞周期中大多数处于 G1 阶段的各种重要基因的遗传表达，抑制组蛋白去乙酰化酶 II 类，从而导致乳腺癌细胞通过凋亡死亡。

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Grouped product items
规格	价格	库存
5mg	¥175.00	现货
10mg	¥315.00	现货
25mg	¥595.00	现货
50mg	¥980.00	现货
100mg	¥1,785.00	现货
200mg	¥3,150.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用MC1568发表的5篇文献

Bopei Cui, .et al. , Signal Transduct Target Ther, 2023, Sep 25;8(1):366 PMID: 37743418

Vivek Bora, .et al. , Can J Physiol Pharmacol, 2021, 6 October

Minoru Ueda, .et al. , Plant Physiol, 2017, Dec; 175(4): 1760-1773 PMID: 29018096

S Ishikawa, .et al. , Int J Cancer., 2014, 135(11): 2528-2536 PMID: 24346863

Usui T, .et al. , Hypertension., 2014, Feb;63(2):397-403 PMID: 24166750

生物活性

Discription

MC1568 is a member of HDAC inhibitors that inhibits the histone deacetylase class II by modifying the genetic expression of various important genes of cell cycle mostly at G1 phase, resulting in the death of breast cancer cells by apoptosis.

Targets

Target	Value

产品信息

目录号	A10560
分子式	C17H15FN2O3
分子量	314.3
CAS号	852475-26-4
SMILES	CN1C=C(C=C1/C=C/C(=O)NO)/C=C/C(=O)C2=CC(=CC=C2)F
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	12 mg/mL (38.18 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	0.5% CMC	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.82 mL	159.08 mL	318.17 mL
0.5 mM	6.36 mL	31.82 mL	63.63 mL
1 mM	3.18 mL	15.91 mL	31.82 mL
5 mM	0.64 mL	3.18 mL	6.36 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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