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MCC950 sodium是一种有效的NLRP3炎性体抑制剂,可抑制IL-1beta的产生,IC50值为7.5 nM。
靶点信息
NLRP3 | ||||
7.5nM |
In vitro | DMSO | Insoluble | |
Water | 77 mg/mL (180.55 mM) | ||
Ethanol | 36 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 23.45 mL | 117.24 mL | 234.49 mL |
0.5 mM | 4.69 mL | 23.45 mL | 46.9 mL |
1 mM | 2.34 mL | 11.72 mL | 23.45 mL |
5 mM | 0.47 mL | 2.34 mL | 4.69 mL |
*The above data is based on the productmolecular weight 426.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A13478 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 426.46 |
Formula | C20H23N2NaO5S |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 256373-96-3 |
Synonyms | CP-456773 sodium, CP 456773 sodium, CP456773 sodium, MCC 950, MCC-950, CRID-3, CRID3, CRID 3 |
SMILES | O=S(C1=CC(C(C)(O)C)=CO1)([N-]C(NC2=C3CCCC3=CC4=C2CCC4)=O)=O.[Na+] |
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