MCC950
目录号: A22097
NLRP3 抑制剂
MCC950(CP-456773,CRID3)是一种强效且选择性的 NLRP3(含有吡啶结构域的NOD样受体家族蛋白3)抑制剂,其在BMDMs(骨髓来源的巨噬细胞)和HMDMs(人类单核细胞来源的巨噬细胞)中的IC50分别为7.5 nM和8.1 nM。
NLRP3 抑制剂
Discription | MCC950 (CP-456773, CRID3) is a potent and selective inhibitor of NLRP3 (NOD-like receptor (NLR) family, pyrin domain-containing protein 3) with IC50 of 7.5 nM and 8.1 nM in BMDMs and HMDMs, respectively. | |||||
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Cell Research |
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目录号 | A22097 |
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分子式 | C20H24N2O5S |
分子量 | 404.48 |
CAS号 | 210826-40-7 |
SMILES | O=S(NC(NC1=C(CCC2)C2=CC3=C1CCC3)=O)(C4=CC(C(C)(O)C)=CO4)=O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2