Meclizine 2HCl
目录号: A11700
Meclizine 是一种人类孕烷X受体(hPXR)激动剂。它具有抗胆碱能、中枢神经系统抑制和局部麻醉效果。其抗呕吐和抗眩晕效果的机制尚未完全明了,但其中枢抗胆碱能特性部分负责这些效果。
Discription | Meclizine is a human pregnane X receptor (hPXR) agonist. It possesses anticholinergic, central nervous system depressant, and local anesthetic effects. Its antiemetic and antivertigo effects are not fully understood, but its central anticholinergic properties are partially responsible. |
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目录号 | A11700 |
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分子式 | C25H29Cl3N2 |
分子量 | 463.87 |
CAS号 | 1104-22-9 |
SMILES | CC1=CC(=CC=C1)CN2CCN(CC2)C(C3=CC=CC=C3)C4=CC=C(C=C4)Cl.Cl.Cl |
其他名称 | Meclozine |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro (25°C) | DMSO | Warmed: 4 mg/mL (8.62 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
In vivo | 5% DMSO+95% Corn oil | 9 mg/mL | |
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 21.56 mL | 107.79 mL | 215.58 mL |
0.5 mM | 4.31 mL | 21.56 mL | 43.12 mL |
1 mM | 2.16 mL | 10.78 mL | 21.56 mL |
5 mM | 0.43 mL | 2.16 mL | 4.31 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2