Mertansine
目录号: A20772
microtubulin 抑制剂
Mertansine(DM1)是一种微管蛋白抑制剂,同时也是一种可与抗体结合的马坦西类化合物,其开发目的是为了克服与马坦西相关的系统性毒性,并增强对肿瘤的特异性传递。
Discription | Mertansine (DM1) is a microtubulin inhibitor and is an antibody-conjugatable maytansinoid that is developed to overcome systemic toxicity associated with maytansine and to enhance tumor-specific delivery. | ||
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目录号 | A20772 |
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分子式 | C35H48ClN3O10S |
分子量 | 738.29 |
CAS号 | 139504-50-0 |
SMILES | C[C@]1([C@@](CC(N(C(C=C2C=C3OC)=C3Cl)C)=O)([H])OC([C@H](C)N(C)C(CCS)=O)=O)[C@H]([C@@H]([C@](OC4=O)([H])C[C@]([C@](/C=C/C=C(C)/C2)([H])OC)(N4)O)C)O1 |
其他名称 | DM1; Maytansinoid DM1 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2