MGCD-265 analog
目录号: A10587
c-Met 抑制剂
MGCD265 是一种多靶点酪氨酸激酶抑制剂,它能结合并抑制多种受体酪氨酸激酶(RTKs)的磷酸化,包括 c-Met 受体(HGFR);Tek/Tie-2 受体;VEGFR 类型 1、2 和 3;以及 MST1R。
Discription | MGCD265 is a multitargeted tyrosine kinase inhibitor that binds to and inhibits the phosphorylation of several RTKs, including the c-Met receptor (HGFR); the Tek/Tie-2 receptor; VEGFR types 1, 2, and 3; and MST1R. | |||||
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Cell Research |
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目录号 | A10587 |
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分子式 | C26H20FN5O2S2 |
分子量 | 517.6 |
CAS号 | 875337-44-3 |
SMILES | CN1C=C(N=C1)C2=CC3=NC=CC(=C3S2)OC4=C(C=C(C=C4)NC(=S)NC(=O)CC5=CC=CC=C5)F |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 99 mg/mL (191.26 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 19.32 mL | 96.6 mL | 193.2 mL |
0.5 mM | 3.86 mL | 19.32 mL | 38.64 mL |
1 mM | 1.93 mL | 9.66 mL | 19.32 mL |
5 mM | 0.39 mL | 1.93 mL | 3.86 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2