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MGL-3196是高度选择性的THR-β激动剂，EC50值为0.21 μM。旨在增加胆固醇向肝脏的吸收并增加其代谢。
| In vitro | DMSO | 80 mg/mL (183.81 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.98 mL | 114.88 mL | 229.77 mL |
| 0.5 mM | 4.6 mL | 22.98 mL | 45.95 mL |
| 1 mM | 2.3 mL | 11.49 mL | 22.98 mL |
| 5 mM | 0.46 mL | 2.3 mL | 4.6 mL |
*The above data is based on the productmolecular weight 435.22. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A13248 |
|---|---|
| 作用机制 | Agonist (激动剂) |
| M. Wt | 435.22 |
| Formula | C17H12Cl2N6O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 920509-32-6 |
| Synonyms | MGL3196, MGL 3196 |
| SMILES | CC(C)c1cc(Oc2c(Cl)cc(cc2Cl)-n2nc(C#N)c(=O)[nH]c2=O)n[nH]c1=O |
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