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MHY1485是mTOR激活剂；通过抑制自噬体和溶酶体之间的融合导致LC3II蛋白的积累和自噬体扩大，从而抑制自噬过程。
靶点信息
| mTOR | ||||
| In vitro | DMSO | 4 mg/mL (10.32 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.81 mL | 129.07 mL | 258.14 mL |
| 0.5 mM | 5.16 mL | 25.81 mL | 51.63 mL |
| 1 mM | 2.58 mL | 12.91 mL | 25.81 mL |
| 5 mM | 0.52 mL | 2.58 mL | 5.16 mL |
*The above data is based on the productmolecular weight 387.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A15508 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 387.39 |
| Formula | C17H21N7O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 326914-06-1 |
| Synonyms | MHY 1485, MHY-1485 |
| SMILES | C1COCCN1C2=NC(=NC(=N2)NC3=CC=C(C=C3)[N+](=O)[O-])N4CCOCC4 |
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