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￥ 0.00 HCV Protease
| Catalog No. | Inhibitor Name | HCV Protease |
|---|---|---|
| A10159 | Daclatasvir (BMS-790052) | **** |
| A10902 | Telaprevir (VX-950) | ** |
| A10980 | Lomibuvir (VX-222, VCH-222) | * |
| A10284 | Danoprevir (ITMN-191) | *** |
| A13155 | Ledipasvir (GS5885) | |
| A11294 | Anguizole | ** |
| A11295 | Asunaprevir (BMS-650032) | **** |
| A11332 | Boceprevir (SCH-503034) | *** |
| A11343 | Ciluprevir (BILN 2061) | *** |
| A11580 | Simeprevir | **** |
Notes:
1.Hover mouse over "" to view the IC50 value.(A few compounds have proven potency but without published IC50 data.)
2.For more details about the compound, click on the product name of your interest.
3.The higher the number of "" is, the more potent the inhibitor or activator is.
4."" refers to compounds which do inhibitory effects on the related isoform, but without specific value.
50 个项目
每页
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MK-5172 hydrate
Catalog No. A15166 -
MK-5172 potassium salt
Catalog No. A15167 -
MK-5172 sodium salt
Catalog No. A15168 -
RO-9187
Catalog No. A15224 -
Nesbuvir
Catalog No. A11510 -
Simeprevir
Catalog No. A11580 HCV NS3/4A protease 抑制剂Simeprevir是HCV NS3/4A蛋白酶（Ki = 0.36 nM）和病毒复制（replicon EC50 = 7.8 nM）的有效抑制剂。 了解更多 -
Vaniprevir
Catalog No. A11600 -
Velpatasvir
Catalog No. A17302 HCV NS5A inhibitorVelpatasvir, also known as GS-5816, is a potent and selective Hepatitis C virus NS5A inhibitor. 了解更多 -
Ombitasvir (ABT-267)
Catalog No. A17624 HCV NS5A inhibitorOmbitasvir is a potent inhibitor of the hepatitis C virus protein NS5A, with EC50s of 0.82 to 19.3 pM against HCV genotypes 1 to 5, and 366 pM against genotype 6a. 了解更多 -
Paritaprevir (ABT-450)
Catalog No. A17625 HCV NS3/4A inhibitorParitaprevir (ABT-450) is a potent non-structural protein 3/4A (NS3/4A) protease inhibitor with EC50s of 1 and 0.21 nM against HCV 1a and 1b, respectively. 了解更多 -
Ledipasvir acetone
Catalog No. A18055 HCV NS5A inhibitorLedipasvir acetone is the active pharmaceutical ingredient of Ledipasvir. Ledipasvir is an inhibitor of the hepatitis C virus NS5A, with EC50 values of 34 pM against GT1a and 4 pM against GT1b replicon. 了解更多 -
Voxilaprevir
Catalog No. A12067 HCV NS 3/4A protease inhibitorVoxilaprevir (GS-9857) is a fluorinated macrocyclic hepatitis C virus (HCV) nonstructural protein (NS) 3/4A protease inhibitor with potent in vitro antiviral activity against genotypes 1-6 HCV and broad coverage of NS3/4A protease polymorphisms. GS-9857 improves coverage against commonly encountered NS3 resistance-associated variants (RAVs). 了解更多 -
Mericitabine
Catalog No. A11539 HCV NS5B polymerase inhibitorMericitabine (RG 7128; R-7128) is a nucleoside inhibitor of the HCV NS5B polymerase that acts as an RNA chain terminator and prevents elongation of RNA transcripts during replication. 了解更多 -
PSI-352938
Catalog No. A21253 HCV nucleotide inhibitorPSI-352938 (PSI-938) is a hepatitis C virus (HCV) nucleotide inhibitor. 了解更多 -
Beclabuvir
Catalog No. A21511 HCV NS5B RNA-dependent RNA polymerase inhibitorBeclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM. 了解更多 -
Sofosbuvir impurity C
Catalog No. A21636 HCV RNA replication inhibitorSofosbuvir impurity C is the less active impurity of Sofosbuvir, Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity. 了解更多 -
Sofosbuvir impurity A
Catalog No. A21641 HCV RNA replication inhibitorSofosbuvir impurity A, an diastereoisomer of sofosbuvir, is the impurity of sofosbuvir. Sofosbuvir (PSI-7977) is an inhibitor of HCV RNA replication, demonstrates potent anti-hepatitis C virus activity. 了解更多 -
PSI-6206 13CD3
Catalog No. A21782 HCV NS5B polymerase inhibitorPSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is the deaminated derivative of PSI-6130, which is a potent and selective inhibitor of HCV NS5B polymerase. 了解更多 -
BMS-790052 (Daclatasvir)
Catalog No. A10159 HCV NS5A 抑制剂BMS-790052 (Daclatasvir)是一种高度选择性的HCV NS5A抑制剂，EC50为9-50 pM，用于治疗丙型肝炎病毒（HCV）感染。 了解更多 -
Danoprevir (RG7227)
Catalog No. A10284 HCV NS3/4A protease 抑制剂Danoprevir (RG7227)是HCV NS3/4A丝氨酸蛋白酶的有效抑制剂。 了解更多 -
Telaprevir (VX-950)
Catalog No. A10902 HCV NS3-4A protease 抑制剂Telaprevir (VX-950)被称为蛋白酶抑制剂，可抑制丙型肝炎病毒NS3.4A丝氨酸蛋白酶。 了解更多 -
Anguizole
Catalog No. A11294 -
Asunaprevir (BMS-650032)
Catalog No. A11295 -
Boceprevir (SCH-503034)
Catalog No. A11332 HCV Protease 抑制剂Boceprevir (SCH-503034)是一种蛋白酶抑制剂，可用于治疗C型肝炎基因型1。 了解更多 -
Balapiravir (R1626)
Catalog No. A11335 Polymerase 抑制剂Balapiravir (R1626)是丙型肝炎病毒(HCV) RNA依赖性rna聚合酶(R1479，RG1479)核苷类似物抑制剂的前药。 了解更多 -
BMS-790052 2HCl
Catalog No. A11336 -
Ciluprevir (BILN 2061)
Catalog No. A11343 HCV NS3 protease 抑制剂Ciluprevir (BILN 2061)是HCV NS3蛋白酶的一种特定而有效的拟肽抑制剂。 了解更多 -
PSI-6130
Catalog No. A11519 -
Tegobuvir (GS-9190)
Catalog No. A11583 -
Setrobuvir (ANA-598)
Catalog No. A13105 -
Celgosivir
Catalog No. A13118 -
MK 8742 (elbasvir)
Catalog No. A13965 -
Glecaprevir
Catalog No. A16948 HCV NS3/4A protease 抑制剂Glecaprevir，也称为ABT-493和A-1282576，是一种新型的HCV NS3/4A蛋白酶抑制剂，IC50值在3.5至11.3 nM之间。 了解更多 -
Narlaprevir
Catalog No. A11506 -
MK-5172
Catalog No. A13787 -
BI207127 (Deleobuvir)
Catalog No. A13414
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