Telaprevir (VX-950)

Name: Telaprevir (VX-950)
SKU: A10902
Price: 245 CNY
Rating: 5 (9 reviews)

目录号: A10902

HCV NS3-4A protease 抑制剂

9 篇发表文献

Telaprevir (VX-950) 被称为蛋白酶抑制剂，它抑制丙型肝炎病毒 NS3.4A 丝氨酸蛋白酶。

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Grouped product items
规格	价格	库存
1mg	¥245.00	现货
2mg	¥385.00	现货
5mg	¥595.00	现货
10mg	¥1,085.00	现货
25mg	¥1,750.00	现货
50mg	¥2,450.00	现货
100mg	¥4,550.00	现货
*10mM 1mL in DMSO**	¥1,190.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Telaprevir (VX-950)发表的9篇文献

Mahim Khan, .et al. , BMC Complement Med Ther, 2022, Apr 2;22(1):98 PMID: 35366855

Adita Ayu Permanasari, .et al. , BMC Complement Med Ther, 2021, Oct 12;21(1):260 PMID: 34641875

Che C Colpitts, .et al. , eLife, 2020, 9: e52237 PMID: 32539931

TS Wahyuni, .et al. , Southeast Asian J Trop Med public health, 2020, 51(1)

Stefan Bittmann, .et al. , J Regen Biol Med, 2020, 2(2):1-3

Wahyuni TS, .et al. , J Basic Clin Physiol Pharmacol, 2019, Dec 14 PMID: 31837259

Jacobs CL, .et al. , Nat Methods, 2018, Jul;15(7):523-526 PMID: 29967496

Apriyanto DR, .et al. , Jpn J Infect Dis, 2016, May 20;69(3):213-20 PMID: 26255732

Mizuki Yamamoto, .et al. , Antimicrob Agents Chemother, 2016, Nov; 60(11): 6532-6539 PMID: 27550352

生物活性

Discription

Telaprevir (VX-950) is known as protease inhibitors that inhibits the hepatitis C virus NS3.4A serine protease.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10902
分子式	C36H53N7O6
分子量	679.9
CAS号	402957-28-2
SMILES	CCC[C@@H](C(=O)C(=O)NC1CC1)NC(=O)[C@@H]2[C@H]3CCC[C@H]3CN2C(=O)[C@H](C(C)(C)C)NC(=O)[C@H](C4CCCCC4)NC(=O)C5=NC=CN=C5
其他名称	VX950, Incivek, Incivo
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	131 mg/mL (192.69 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	14.71 mL	73.54 mL	147.08 mL
0.5 mM	2.94 mL	14.71 mL	29.42 mL
1 mM	1.47 mL	7.35 mL	14.71 mL
5 mM	0.29 mL	1.47 mL	2.94 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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