Mirabegron

Name: Mirabegron
SKU: A12861

目录号: A12861

β3 adrenergic receptor activator

Product Citations (1)

Mirabegron Chemical Structure

CAS NO. 223673-61-8

Mirabegron是一种选择性的beta3-adrenoceptor（β3肾上腺素受体）激动剂，EC50为22.4 nM。是有效的膀胱松弛药和糖尿病药物。

库存：现货

规格	价格	数量
5 mg	￥ 560.00
10 mg	￥ 980.00
25 mg	￥ 1,960.00
50 mg	￥ 3,150.00
10mM * 1mL in DMSO	￥ 854.00

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生物活性

Mirabegron是一种选择性的beta3-adrenoceptor（β3肾上腺素受体）激动剂，EC50为22.4 nM。是有效的膀胱松弛药和糖尿病药物。

靶点信息

β3-adrenoceptor
22.4 nM(EC50)

溶解度 *

In vitro (25°C)	DMSO	70 mg/mL (176.53 mM)
	Water	Insoluble
	Ethanol	7 mg/mL (17.65 mM)
In vivo	2% DMSO+30% PEG 300+ddH2O	10 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.22 mL	126.1 mL	252.2 mL
0.5 mM	5.04 mL	25.22 mL	50.44 mL
1 mM	2.52 mL	12.61 mL	25.22 mL
5 mM	0.5 mL	2.52 mL	5.04 mL

*The above data is based on the productmolecular weight 396.51. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12861
作用机制	Activator (激活剂)
M. Wt	396.51
Formula	C21H24N4O2S
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	223673-61-8
SMILES	C1=CC=C(C=C1)[C@H](CNCCC2=CC=C(C=C2)NC(=O)CC3=CSC(=N3)N)O