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Mirogabalin besylate is a selective and orally available ligand for the α2δ subunit of voltage-gated calcium channels, with Kds of 13.5 nM, 22.7 nM, 27 nM, and 47.6 nM for human α2δ-1, human α2δ-2, rat α2δ-1, and rat α2δ-2, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 27.21 mL | 136.07 mL | 272.14 mL |
| 0.5 mM | 5.44 mL | 27.21 mL | 54.43 mL |
| 1 mM | 2.72 mL | 13.61 mL | 27.21 mL |
| 5 mM | 0.54 mL | 2.72 mL | 5.44 mL |
*The above data is based on the productmolecular weight 367.46. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A19379 |
|---|---|
| M. Wt | 367.46 |
| Formula | C18H25NO5S |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1138245-21-2 |
| Synonyms | DS 5565 besylate, DS5565, DS-5565 |
| SMILES | O=S(C1=CC=CC=C1)(O)=O.OC(C[C@@]2([C@@]3([H])[C@@](CC(CC)=C3)([H])C2)CN)=O |
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